General Cell Lines and Cell Cultures
ATCC Shigella flexneri; 2457T; genomic DNA
Genomic DNA isolated from Shigella flexneri strain 2457T (ATCC 700930). The presence of the plasmid pINV-2457T has not been confirmed.
Biochain Institute Inc Frozen Tissue Section - Arteriosclerosis Artery and Matched Non-arteriosclerosis Artery, 2 x 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. The tissues are immediately put in liquid nitrogen after being excised, and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. BioChain's frozen tissue section line encompasses a large selection of tissue sections which are good for immunohistochemistry and in situ hybridization. The tissue sections are approximately 5-10 um thick.
Eurofins Discoverx ChemiBrite TP Prostanoid Receptor Stable Cell Line, 2 vials. (HTS081L)
The ChemiBrite TP Prostanoid Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin H2, thromboxane A2) based activation of TBXA2R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TBXA2R alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of TBXA2R, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PrecisION hKv4.3/hKChIP2 Recombinant Stable Cell Line, 2 vials. (CYL3069)
The PrecisION hKv4.3/hKChIP2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv4.3/KChIP2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv4.3/KChIP2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx PathHunter CHO-K1 GPR84 β-Arrestin Cell Line, 2 vials. (93-0647C2)
The PathHunter GPR84 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of GPR84 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR84 and EA-tagged β-Arrestin-2. Activation of GPR84 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC Lyophilized microvesicles from NCI-H1975 cell line
Lyophilized microvesicles from NCI-H1975 cell line
ATCC Bifidobacterium adolescentis
Bifidobacterium adolescentis strain E194a (Variant a) is a whole-genome sequenced type strain that was isolated from the intestine of an adult. It has applications in bioinformatics and is a microbiome standard component.
ATCC NCI-H1568; Lung Adenocarcinoma; Human (Homo sapiens)
NCI-H1568 [H1568] cells were isolated from the lungs of a 48-year-old, White female patient with non-small cell lung cancer: adenocarcinoma. This product has applications in cancer research.
Medchemexpress LLC GLP1R protein, human (HEK293, N-His, C-Myc) | >95.0% | 100UG
Recombinant human GLP1R protein expressed in HEK293 cells and supplied lyophilized with N-terminal His and C-terminal C-Myc tags. The glycosylated receptor is functional in ligand-binding assays, activates adenylyl cyclase to increase intracellular cAMP upon ligand binding, and is suitable for biochemical characterization, antibody validation, and receptor-ligand interaction studies.
- Expressed in HEK293 cells.
- N-His and C-Myc tagged for detection and purification.
- Glycosylated; apparent molecular weight ~25-38 kDa.
- Purity >95% by reducing SDS-PAGE.
- Available in 20 μg, 50 μg, and 100 μg quantities.
- Lyophilized formulation with trehalose for stability.
- Store at -20°C; reconstituted material stable at 4°C for one week.
Eurofins Discoverx PathHunter U2OS rHTR2C β-Arrestin Cell Line, 2 vials. (93-0915C3)
The PathHunter rHTR2C cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of rHTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rHTR2C and EA-tagged β-Arrestin-2. Activation of rHTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Frontal Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.